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Agios Pharmaceuticals (AGIO) Q1 2026 earnings results (first quarter 2026)

10-Q filed Apr 29, 2026

Agios Pharmaceuticals (AGIO) reported revenue of $20.7M for the first quarter 2026 (Q1 2026), +138% from a year earlier and +4% from the quarter before. Operating margin was -530.3%, net loss $99.1M (477.7% of revenue).

Revenue$20.7M
Year over year+138%
Quarter over quarter+4%
Operating margin-530.3%
Net earnings−$99.1M

Agios Pharmaceuticals, Q1 2026: revenue $20.7M (+138% year over year), operating margin -530.3%, net loss $99.1M, operating cash flow −$119M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$20.7M+4%+138%
Operating profit−$110M——
Net earnings−$99.1M——
Operating cash flow−$119M——

What changed

Revenue was $20.7M in Q1 2026, up 138% year over year and up 4% from the previous quarter.

Operating costs exceeded revenue by $110.0M, an operating margin of -530.3%. Total costs grew 13% against revenue growth of 138%. The fastest-growing cost line was Cost of revenue (+22%). The quarter ended with a net loss of $99.1M, narrower than the previous quarter's $108.0M loss.

Operating cash flow was −$118.9M. Non-cash charges added back $15.5M of share-based compensation. Working capital and other items used $35.4M. Capital expenditures of $769K exceeded it, leaving free cash flow of −$119.7M.

Questions

What was Agios Pharmaceuticals' revenue in the first quarter 2026?

Agios Pharmaceuticals (AGIO) reported revenue of $20.7M for the first quarter 2026 (Q1 2026), +138% from a year earlier and +4% from the quarter before.

Was Agios Pharmaceuticals profitable in the first quarter 2026?

Operating loss was $110M (-530.3% of revenue) and net loss $99.1M.

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Source: Agios Pharmaceuticals 10-Q on SEC EDGAR.