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Agios Pharmaceuticals (AGIO) Q3 2025 earnings results (third quarter 2025)

10-Q filed Oct 30, 2025

Agios Pharmaceuticals (AGIO) reported revenue of $12.9M for the third quarter 2025 (Q3 2025), +44% from a year earlier and +3% from the quarter before. Operating margin was -907.4%, net loss $103M (803.1% of revenue).

Revenue$12.9M
Year over year+44%
Quarter over quarter+3%
Operating margin-907.4%
Net earnings−$103M

Agios Pharmaceuticals, Q3 2025: revenue $12.9M (+44% year over year), operating margin -907.4%, net loss $103M, operating cash flow −$88.2M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$12.9M+3%+44%
Operating profit−$117M——
Net earnings−$103M——
Operating cash flow−$88.2M——

What changed

Revenue was $12.9M in Q3 2025, up 44% year over year and up 3% from the previous quarter.

Operating costs exceeded revenue by $116.9M, an operating margin of -907.4%. Total costs grew 16% against revenue growth of 44%. The fastest-growing cost line was Cost of revenue (+114%). The quarter ended with a net loss of $103.4M, narrower than the previous quarter's $112.0M loss.

Operating cash flow was −$88.2M. Non-cash charges added back $12.4M of share-based compensation. Capital expenditures of $1.6M exceeded it, leaving free cash flow of −$89.7M.

Questions

What was Agios Pharmaceuticals' revenue in the third quarter 2025?

Agios Pharmaceuticals (AGIO) reported revenue of $12.9M for the third quarter 2025 (Q3 2025), +44% from a year earlier and +3% from the quarter before.

Was Agios Pharmaceuticals profitable in the third quarter 2025?

Operating loss was $117M (-907.4% of revenue) and net loss $103M.

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Source: Agios Pharmaceuticals 10-Q on SEC EDGAR.