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Is Agios Pharmaceuticals (AGIO) a takeover target?

A leveraged buyout does not work for Agios Pharmaceuticals on its latest figures: it has no positive EBITDA to borrow against (−$454M over the last 12 months, on revenue of $98.3M). Historically 6.0% of companies with its figures were bought within a year (1.19× the average).

Share price$31.81
Market value$1.9B
Enterprise value$1.3B
Cash$618M
Debt$0
Revenue, 12 months$98.3M
Revenue growth+141%
EBITDA, 12 months−$454M

Why a leveraged buyout does not fit

A leveraged buyout is paid for mostly with debt that the company's own cash flow repays. Agios Pharmaceuticals' EBITDA over the last 12 months was −$454M on revenue of $98.3M, so there is nothing to lend against and nothing to repay a loan with: a buyer would have to pay almost entirely with its own money. That is the kind of deal another company — a strategic buyer that wants the products, the pipeline or the technology — makes, not a private-equity fund. The model therefore gives no buyout price.

What a takeover could cost

Takeovers in its sector paid a median premium of 35% over the share price before the deal (the middle half 22% to 45%), according to the 15 merger proxies and tender-offer responses on EDGAR that state a premium. At the median, Agios Pharmaceuticals would cost about $42.94 a share, $2.6B for all its shares.

Premium%Price a shareAll shares
Low end (a quarter of deals paid less)22%$38.81$2.3B
Median35%$42.94$2.6B
High end (a quarter paid more)45%$46.12$2.7B

The odds, from history

Historically 6.0% of companies with its figures were bought within a year (1.19× the average). Its figures put it in decile 8 of 10 (10 = the most likely to be bought). The odds come from a model of every merger proxy, tender-offer response and going-private statement filed on EDGAR since 2011, set against each company's size, margins, debt, cash flow and growth the year before.

Agios Pharmaceuticals' latest quarter

Agios Pharmaceuticals, Q3 2026: revenue $55.4M (+330% year over year), operating margin -139.3%, net loss $65.0M, operating cash flow −$59.2M. The chart follows the revenue to costs, profit and cash.

Questions

Is Agios Pharmaceuticals being acquired?

No headline, 8-K or 13D about a sale is on file in the last year.

Could private equity buy Agios Pharmaceuticals?

A leveraged buyout does not work for Agios Pharmaceuticals on its latest figures: it has no positive EBITDA to borrow against (−$454M over the last 12 months, on revenue of $98.3M). With no cash flow to repay a loan, a buyer would pay almost entirely with its own money: a deal for another company (a strategic buyer), not for a private-equity fund.

What would a takeover of Agios Pharmaceuticals cost?

Takeovers in its sector paid a median premium of 35% over the share price before the deal (the middle half 22% to 45%), according to the 15 merger proxies and tender-offer responses on EDGAR that state a premium. At the median, Agios Pharmaceuticals would cost about $42.94 a share, $2.6B for all its shares.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.