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Alector (ALEC) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 7, 2025

Alector (ALEC) reported revenue of $7.9M for the second quarter 2025 (Q2 2025), -48% from a year earlier and +113% from the quarter before. Operating margin was -433.6%, net loss $30.5M (387.7% of revenue).

Revenue$7.9M
Year over year-48%
Quarter over quarter+113%
Operating margin-433.6%
Net earnings−$30.5M

Alector, Q2 2025: revenue $7.9M (-48% year over year), operating margin -433.6%, net loss $30.5M, operating cash flow −$49.0M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$7.9M+113%-48%
Operating profit−$34.1M——
Net earnings−$30.5M——
Operating cash flow−$49.0M——

What changed

Revenue was $7.9M in Q2 2025, down 48% year over year and up 113% from the previous quarter.

Operating costs exceeded revenue by $34.1M, an operating margin of -433.6%. Total costs fell 31% while revenue fell 48%. The quarter ended with a net loss of $30.5M, narrower than the previous quarter's $40.5M loss.

Operating cash flow was −$49.0M. Non-cash charges added back $2.3M of depreciation and amortization and $7.1M of share-based compensation. Working capital and other items used $27.9M. Capital expenditures of $10K exceeded it, leaving free cash flow of −$49.1M.

Questions

What was Alector's revenue in the second quarter 2025?

Alector (ALEC) reported revenue of $7.9M for the second quarter 2025 (Q2 2025), -48% from a year earlier and +113% from the quarter before.

Was Alector profitable in the second quarter 2025?

Operating loss was $34.1M (-433.6% of revenue) and net loss $30.5M.

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Source: Alector 10-Q on SEC EDGAR.