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Amphastar Pharmaceuticals (AMPH) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 26, 2026

Amphastar Pharmaceuticals (AMPH) reported revenue of $183M for the fourth quarter 2025 (Q4 2025), -2% from a year earlier and -5% from the quarter before. Operating margin was 19.4%, net earnings $24.4M (13.3% of revenue).

Revenue$183M
Year over year-2%
Quarter over quarter-5%
Operating margin19.4%
Net earnings$24.4M

Amphastar Pharmaceuticals, Q4 2025: revenue $183M (-2% year over year), operating margin 19.4%, net earnings $24.4M, operating cash flow $32.9M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$183M-5%-2%
Gross profit$85.7M-13%-1%
Operating profit$35.6M+41%-21%
Net earnings$24.4M+41%-36%
Operating cash flow$32.9M-38%+13%
Free cash flow$24.6M-48%+48%

What changed

Revenue was $183.1M in Q4 2025, down 2% year over year and down 5% from the previous quarter.

Gross margin was 46.8%, up 0.3 points from a year earlier. Operating profit was $35.6M, a 19.4% margin (down 4.8 points year over year). Operating expenses grew 21% against a revenue fall of 2%. The fastest-growing cost line was Research & development (+29%). Net earnings were $24.4M, down 36% year over year. The effective tax rate was 23.5%.

Operating cash flow was $32.9M (up 13% year over year), 135% of net earnings. Non-cash charges added back $14.3M of depreciation and amortization and $6.2M of share-based compensation. Working capital and other items used $12.1M. Capital expenditures of $8.3M left free cash flow of $24.6M.

Questions

What was Amphastar Pharmaceuticals' revenue in the fourth quarter 2025?

Amphastar Pharmaceuticals (AMPH) reported revenue of $183M for the fourth quarter 2025 (Q4 2025), -2% from a year earlier and -5% from the quarter before.

Was Amphastar Pharmaceuticals profitable in the fourth quarter 2025?

Operating profit was $35.6M (19.4% of revenue) and net earnings $24.4M.

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Source: Amphastar Pharmaceuticals 10-K on SEC EDGAR.