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Arrowhead Pharmaceuticals (ARWR) Q4 FY25 earnings results (fourth quarter fiscal 2025)

10-K filed Nov 25, 2025

Arrowhead Pharmaceuticals (ARWR) reported revenue of $256M for the fourth quarter fiscal 2025 (Q4 FY25) and +824% from the quarter before. Operating margin was 17.2%, net earnings $16.1M (6.3% of revenue).

Revenue$256M
Year over year—
Quarter over quarter+824%
Operating margin17.2%
Net earnings$16.1M

Arrowhead Pharmaceuticals, Q4 FY25: revenue $256M, operating margin 17.2%, net earnings $16.1M, operating cash flow $20.5M. The chart follows the revenue to costs, profit and cash.

Q4 FY25AmountQ/QY/Y
Revenue$256M+824%—
Operating profit$44.1M——
Net earnings$16.1M——
Operating cash flow$20.5M——
Free cash flow$13.0M——

What changed

Revenue was $256.5M in Q4 FY25, up 824% from the previous quarter.

Operating profit was $44.1M, a 17.2% margin. Net earnings were −$23.8M. The effective tax rate was 55.4%.

Operating cash flow was $20.5M, 127% of net income including minority interests. Non-cash charges added back $6.0M of depreciation and amortization and $19.1M of share-based compensation. Working capital and other items used $20.7M. Capital expenditures of $7.5M left free cash flow of $13.0M.

Questions

What was Arrowhead Pharmaceuticals' revenue in the fourth quarter fiscal 2025?

Arrowhead Pharmaceuticals (ARWR) reported revenue of $256M for the fourth quarter fiscal 2025 (Q4 FY25) and +824% from the quarter before.

Was Arrowhead Pharmaceuticals profitable in the fourth quarter fiscal 2025?

Operating profit was $44.1M (17.2% of revenue) and net earnings $16.1M.

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Source: Arrowhead Pharmaceuticals 10-K on SEC EDGAR.