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Assembly Biosciences (ASMB) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 10, 2025

Assembly Biosciences (ASMB) reported revenue of $10.8M for the third quarter 2025 (Q3 2025), +58% from a year earlier and +12% from the quarter before. Operating margin was -100.9%, net loss $9.2M (85.2% of revenue).

Revenue$10.8M
Year over year+58%
Quarter over quarter+12%
Operating margin-100.9%
Net earnings−$9.2M

Assembly Biosciences, Q3 2025: revenue $10.8M (+58% year over year), operating margin -100.9%, net loss $9.2M, operating cash flow −$15.1M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$10.8M+12%+58%
Operating profit−$10.9M——
Net earnings−$9.2M——
Operating cash flow−$15.1M——

What changed

Revenue was $10.8M in Q3 2025, up 58% year over year and up 12% from the previous quarter.

Operating costs exceeded revenue by $10.9M, an operating margin of -100.9%. Total costs grew 22% against revenue growth of 58%. The fastest-growing cost line was Research & development (+23%). The quarter ended with a net loss of $9.2M, narrower than the previous quarter's $10.2M loss.

Operating cash flow was −$15.1M. Non-cash charges added back $32K of depreciation and amortization and $1.7M of share-based compensation. Working capital and other items used $7.6M. Capital expenditures of $42K exceeded it, leaving free cash flow of −$15.2M.

Questions

What was Assembly Biosciences' revenue in the third quarter 2025?

Assembly Biosciences (ASMB) reported revenue of $10.8M for the third quarter 2025 (Q3 2025), +58% from a year earlier and +12% from the quarter before.

Was Assembly Biosciences profitable in the third quarter 2025?

Operating loss was $10.9M (-100.9% of revenue) and net loss $9.2M.

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Source: Assembly Biosciences 10-Q on SEC EDGAR.