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ASP Isotopes (ASPI) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Apr 10, 2026

ASP Isotopes (ASPI) reported revenue of $16.7M for the fourth quarter 2025 (Q4 2025), up 14-fold from a year earlier and +241% from the quarter before. Operating margin was -150.2%, net loss $63.3M (380.1% of revenue).

Revenue$16.7M
Year over year14×
Quarter over quarter+241%
Operating margin-150.2%
Net earnings−$63.3M

ASP Isotopes, Q4 2025: revenue $16.7M (14× year over year), operating margin -150.2%, net loss $63.3M, operating cash flow −$17.9M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$16.7M+241%14×
Operating profit−$25.0M——
Net earnings−$63.3M——
Operating cash flow−$17.9M——

What changed

Revenue was $16.7M in Q4 2025, up 1296% year over year and up 241% from the previous quarter.

Gross margin was 12.5%, down 38.2 points from Q4 2024. Operating costs exceeded revenue by $25.0M, an operating margin of -150.2%. Operating expenses grew 228% against revenue growth of 1296%. The fastest-growing cost line was Research & development (+384%). The quarter ended with a net loss of $63.3M, wider than the previous quarter's $12.9M loss. Net interest and other expense of $38.1M was the main reason.

Operating cash flow was −$17.9M. Non-cash charges added back $937K of depreciation and amortization and $5.2M of share-based compensation. Working capital and other items added $39.3M. Capital expenditures of $2.4M exceeded it, leaving free cash flow of −$20.2M.

Questions

What was ASP Isotopes' revenue in the fourth quarter 2025?

ASP Isotopes (ASPI) reported revenue of $16.7M for the fourth quarter 2025 (Q4 2025), up 14-fold from a year earlier and +241% from the quarter before.

Was ASP Isotopes profitable in the fourth quarter 2025?

Operating loss was $25.0M (-150.2% of revenue) and net loss $63.3M.

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Source: ASP Isotopes 10-K on SEC EDGAR.