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Axogen (AXGN) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 24, 2026

Axogen (AXGN) reported revenue of $59.9M for the fourth quarter 2025 (Q4 2025), +21% from a year earlier and -0.3% from the quarter before. Operating margin was -16.3%, net loss $13.2M (22.0% of revenue).

Revenue$59.9M
Year over year+21%
Quarter over quarter-0.3%
Operating margin-16.3%
Net earnings−$13.2M

Axogen, Q4 2025: revenue $59.9M (+21% year over year), operating margin -16.3%, net loss $13.2M, operating cash flow $3.0M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$59.9M-0.3%+21%
Operating profit−$9.8M-611%—
Net earnings−$13.2M-1958%—
Operating cash flow$3.0M-6%-65%
Free cash flow$1.8M+5%-78%

What changed

Revenue was $59.9M in Q4 2025, up 21% year over year and roughly flat from the previous quarter.

Gross margin was 74.1%, down 1.9 points from a year earlier. Operating costs exceeded revenue by $9.8M, an operating margin of -16.3%. Operating expenses grew 52% against revenue growth of 21%. The fastest-growing cost line was Research & development (+85%). The quarter ended with a net loss of $13.2M, after a profit of $708K the previous quarter.

Operating cash flow was $3.0M (down 65% year over year). Non-cash charges added back $1.7M of depreciation and amortization and $16.6M of share-based compensation. Working capital and other items used $2.1M. Capital expenditures of $1.2M left free cash flow of $1.8M.

Questions

What was Axogen's revenue in the fourth quarter 2025?

Axogen (AXGN) reported revenue of $59.9M for the fourth quarter 2025 (Q4 2025), +21% from a year earlier and -0.3% from the quarter before.

Was Axogen profitable in the fourth quarter 2025?

Operating loss was $9.8M (-16.3% of revenue) and net loss $13.2M.

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Source: Axogen 10-K on SEC EDGAR.