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Bicycle Therapeutics (BCYC) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 1, 2025

Bicycle Therapeutics (BCYC) reported revenue of $10.0M for the first quarter 2025 (Q1 2025), -49% from a year earlier and +169% from the quarter before. Operating margin was -703.7%, net loss $60.8M (608.9% of revenue).

Revenue$10.0M
Year over year-49%
Quarter over quarter+169%
Operating margin-703.7%
Net earnings−$60.8M

Bicycle Therapeutics, Q1 2025: revenue $10.0M (-49% year over year), operating margin -703.7%, net loss $60.8M, operating cash flow −$86.4M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$10.0M+169%-49%
Operating profit−$70.2M——
Net earnings−$60.8M——
Operating cash flow−$86.4M——

What changed

Revenue was $10.0M in Q1 2025, down 49% year over year and up 169% from the previous quarter.

Operating costs exceeded revenue by $70.2M, an operating margin of -703.7%. Total costs grew 56% against a revenue fall of 49%. The fastest-growing cost line was Research & development (+69%). The quarter ended with a net loss of $60.8M, wider than the previous quarter's $51.9M loss.

Operating cash flow was −$86.4M. Non-cash charges added back $1.6M of depreciation and amortization and $9.6M of share-based compensation. Working capital and other items used $36.9M. Capital expenditures of $604K exceeded it, leaving free cash flow of −$87.0M.

Questions

What was Bicycle Therapeutics' revenue in the first quarter 2025?

Bicycle Therapeutics (BCYC) reported revenue of $10.0M for the first quarter 2025 (Q1 2025), -49% from a year earlier and +169% from the quarter before.

Was Bicycle Therapeutics profitable in the first quarter 2025?

Operating loss was $70.2M (-703.7% of revenue) and net loss $60.8M.

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Source: Bicycle Therapeutics 10-Q on SEC EDGAR.