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Bicycle Therapeutics (BCYC) Q3 2025 earnings results (third quarter 2025)

10-Q filed Oct 30, 2025

Bicycle Therapeutics (BCYC) reported revenue of $11.7M for the third quarter 2025 (Q3 2025), +338% from a year earlier and +302% from the quarter before. Operating margin was -558.6%, net loss $59.1M (503.7% of revenue).

Revenue$11.7M
Year over year+338%
Quarter over quarter+302%
Operating margin-558.6%
Net earnings−$59.1M

Bicycle Therapeutics, Q3 2025: revenue $11.7M (+338% year over year), operating margin -558.6%, net loss $59.1M, operating cash flow −$71.2M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$11.7M+302%+338%
Operating profit−$65.6M——
Net earnings−$59.1M——
Operating cash flow−$71.2M——

What changed

Revenue was $11.7M in Q3 2025, up 338% year over year and up 302% from the previous quarter.

Operating costs exceeded revenue by $65.6M, an operating margin of -558.6%. Total costs grew 16% against revenue growth of 338%. The fastest-growing cost line was Research & development (+21%). The quarter ended with a net loss of $59.1M, narrower than the previous quarter's $79.0M loss.

Operating cash flow was −$71.2M. Non-cash charges added back $1.8M of depreciation and amortization and $8.8M of share-based compensation. Working capital and other items used $22.6M. Capital expenditures of $674K exceeded it, leaving free cash flow of −$71.8M.

Questions

What was Bicycle Therapeutics' revenue in the third quarter 2025?

Bicycle Therapeutics (BCYC) reported revenue of $11.7M for the third quarter 2025 (Q3 2025), +338% from a year earlier and +302% from the quarter before.

Was Bicycle Therapeutics profitable in the third quarter 2025?

Operating loss was $65.6M (-558.6% of revenue) and net loss $59.1M.

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Source: Bicycle Therapeutics 10-Q on SEC EDGAR.