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C4 Therapeutics (CCCC) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 12, 2026

C4 Therapeutics (CCCC) reported revenue of $6.2M for the first quarter 2026 (Q1 2026), -15% from a year earlier and -44% from the quarter before. Operating margin was -451.6%, net loss $25.1M (408.5% of revenue).

Revenue$6.2M
Year over year-15%
Quarter over quarter-44%
Operating margin-451.6%
Net earnings−$25.1M

C4 Therapeutics, Q1 2026: revenue $6.2M (-15% year over year), operating margin -451.6%, net loss $25.1M, operating cash flow −$29.9M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$6.2M-44%-15%
Operating profit−$27.8M——
Net earnings−$25.1M——
Operating cash flow−$29.9M——

What changed

Revenue was $6.2M in Q1 2026, down 15% year over year and down 44% from the previous quarter.

Operating costs exceeded revenue by $27.8M, an operating margin of -451.6%. Total costs fell 7% while revenue fell 15%. The quarter ended with a net loss of $25.1M, wider than the previous quarter's $20.5M loss.

Operating cash flow was −$29.9M. Non-cash charges added back $404K of depreciation and amortization and $2.7M of share-based compensation. Working capital and other items used $7.9M. Capital expenditures of $64K exceeded it, leaving free cash flow of −$30.0M.

Questions

What was C4 Therapeutics' revenue in the first quarter 2026?

C4 Therapeutics (CCCC) reported revenue of $6.2M for the first quarter 2026 (Q1 2026), -15% from a year earlier and -44% from the quarter before.

Was C4 Therapeutics profitable in the first quarter 2026?

Operating loss was $27.8M (-451.6% of revenue) and net loss $25.1M.

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Source: C4 Therapeutics 10-Q on SEC EDGAR.