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C4 Therapeutics (CCCC) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 7, 2025

C4 Therapeutics (CCCC) reported revenue of $6.5M for the second quarter 2025 (Q2 2025), -46% from a year earlier and -11% from the quarter before. Operating margin was -441.0%, net loss $26.0M (402.6% of revenue).

Revenue$6.5M
Year over year-46%
Quarter over quarter-11%
Operating margin-441.0%
Net earnings−$26.0M

C4 Therapeutics, Q2 2025: revenue $6.5M (-46% year over year), operating margin -441.0%, net loss $26.0M, operating cash flow −$12.1M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$6.5M-11%-46%
Operating profit−$28.5M——
Net earnings−$26.0M——
Operating cash flow−$12.1M——

What changed

Revenue was $6.5M in Q2 2025, down 46% year over year and down 11% from the previous quarter.

Operating costs exceeded revenue by $28.5M, an operating margin of -441.0%. Total costs grew 5% against a revenue fall of 46%. The fastest-growing cost line was Research & development (+10%). The quarter ended with a net loss of $26.0M, narrower than the previous quarter's $26.3M loss.

Operating cash flow was −$12.1M. Non-cash charges added back $615K of depreciation and amortization and $5.0M of share-based compensation. Working capital and other items added $8.4M. Capital expenditures of $185K exceeded it, leaving free cash flow of −$12.2M.

Questions

What was C4 Therapeutics' revenue in the second quarter 2025?

C4 Therapeutics (CCCC) reported revenue of $6.5M for the second quarter 2025 (Q2 2025), -46% from a year earlier and -11% from the quarter before.

Was C4 Therapeutics profitable in the second quarter 2025?

Operating loss was $28.5M (-441.0% of revenue) and net loss $26.0M.

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Source: C4 Therapeutics 10-Q on SEC EDGAR.