Filing Flows › CareDx (CDNA) › Q4 2025
CareDx (CDNA) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Feb 25, 2026
CareDx (CDNA) reported revenue of $108M for the fourth quarter 2025 (Q4 2025), +25% from a year earlier and +8% from the quarter before. Operating margin was -5.6%, net loss $4.1M (3.8% of revenue).
CareDx, Q4 2025: revenue $108M (+25% year over year), operating margin -5.6%, net loss $4.1M, operating cash flow $21.4M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $108M | +8% | +25% |
| Operating profit | −$6.0M | — | — |
| Net earnings | −$4.1M | -345% | — |
| Operating cash flow | $21.4M | -43% | -2% |
| Free cash flow | $19.4M | — | -5% |
What changed
Revenue was $108.4M in Q4 2025, up 25% year over year and up 8% from the previous quarter. Testing services revenue was the largest line at 72% of revenue.
Operating costs exceeded revenue by $6.0M, an operating margin of -5.6%. Total costs grew 5101% against revenue growth of 25%. The quarter ended with a net loss of $4.1M, after a profit of $1.7M the previous quarter. Non-operating items added $2.3M, -61% of pre-tax earnings, so the bottom line overstates operating performance.
Operating cash flow was $21.4M (down 2% year over year). Non-cash charges added back $3.9M of depreciation and amortization and $8.1M of share-based compensation. Working capital and other items added $13.5M. Capital expenditures of $2.0M left free cash flow of $19.4M.
Questions
What was CareDx's revenue in the fourth quarter 2025?
CareDx (CDNA) reported revenue of $108M for the fourth quarter 2025 (Q4 2025), +25% from a year earlier and +8% from the quarter before.
Was CareDx profitable in the fourth quarter 2025?
Operating loss was $6.0M (-5.6% of revenue) and net loss $4.1M.
Source: CareDx 10-K on SEC EDGAR.