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Codexis (CDXS) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 13, 2025

Codexis (CDXS) reported revenue of $15.3M for the second quarter 2025 (Q2 2025), +92% from a year earlier and +103% from the quarter before. Operating margin was -83.9%, net loss $13.3M (86.6% of revenue).

Revenue$15.3M
Year over year+92%
Quarter over quarter+103%
Operating margin-83.9%
Net earnings−$13.3M

Codexis, Q2 2025: revenue $15.3M (+92% year over year), operating margin -83.9%, net loss $13.3M, operating cash flow −$18.0M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$15.3M+103%+92%
Operating profit−$12.9M——
Net earnings−$13.3M——
Operating cash flow−$18.0M——

What changed

Revenue was $15.3M in Q2 2025, up 92% year over year and up 103% from the previous quarter. Research and development revenue was the largest line at 52% of revenue. Research and development revenue added $6.2M year over year (up 362%), 85% of the total change.

Operating costs exceeded revenue by $12.9M, an operating margin of -83.9%. Total costs fell 8% while revenue rose 92%. The fastest-growing cost line was Research & development (+21%). The quarter ended with a net loss of $13.3M, narrower than the previous quarter's $20.7M loss.

Operating cash flow was −$18.0M. Non-cash charges added back $1.3M of depreciation and amortization and $2.5M of share-based compensation. Working capital and other items used $8.6M. Capital expenditures of $2.5M exceeded it, leaving free cash flow of −$20.5M.

Questions

What was Codexis' revenue in the second quarter 2025?

Codexis (CDXS) reported revenue of $15.3M for the second quarter 2025 (Q2 2025), +92% from a year earlier and +103% from the quarter before.

Was Codexis profitable in the second quarter 2025?

Operating loss was $12.9M (-83.9% of revenue) and net loss $13.3M.

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Source: Codexis 10-Q on SEC EDGAR.