Filing Flows › Clene (CLNN) › Q4 2025
Clene (CLNN) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Mar 17, 2026
Clene (CLNN) reported revenue of $77K for the fourth quarter 2025 (Q4 2025), -15% from a year earlier and +413% from the quarter before.
Clene, Q4 2025: revenue $77K (-15% year over year), net loss $9.2M, operating cash flow −$4.8M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $77K | +413% | -15% |
| Operating profit | −$7.5M | — | — |
| Net earnings | −$9.2M | — | — |
| Operating cash flow | −$4.8M | — | — |
What changed
Revenue was $77K in Q4 2025, down 15% year over year and up 413% from the previous quarter. Product was the largest line at 70% of revenue.
Operating costs exceeded revenue by $7.5M, an operating margin of -9733.8%. Total costs fell 13% while revenue fell 15%. The fastest-growing cost line was Cost of revenue (+28%). The quarter ended with a net loss of $9.2M, wider than the previous quarter's $8.8M loss.
Operating cash flow was −$4.8M. Non-cash charges added back $360K of depreciation and $1.4M of share-based compensation. Working capital and other items added $2.7M. Capital expenditures of $28K exceeded it, leaving free cash flow of −$4.8M.
Questions
What was Clene's revenue in the fourth quarter 2025?
Clene (CLNN) reported revenue of $77K for the fourth quarter 2025 (Q4 2025), -15% from a year earlier and +413% from the quarter before.
Source: Clene 10-K on SEC EDGAR.