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Centene (CNC) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 17, 2026

Centene (CNC) reported revenue of $49.7B for the fourth quarter 2025 (Q4 2025), +22% from a year earlier and +0.1% from the quarter before. Operating margin was -3.5%, net loss $1.1B (2.2% of revenue).

Revenue$49.7B
Year over year+22%
Quarter over quarter+0.1%
Operating margin-3.5%
Net earnings−$1.1B

Centene, Q4 2025: revenue $49.7B (+22% year over year), operating margin -3.5%, net loss $1.1B, operating cash flow $437M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$49.7B+0.1%+22%
Operating profit−$1.7B——
Net earnings−$1.1B——
Operating cash flow$437M-68%—
Free cash flow$224M-80%—

What changed

Revenue was $49.7B in Q4 2025, up 22% year over year and roughly flat from the previous quarter. Medicaid was the largest line at 56% of revenue.

Gross margin was 5.1%, down 4.2 points from a year earlier. Operating costs exceeded revenue by $1.7B, an operating margin of -3.5%. Operating expenses grew 19% against revenue growth of 22%. The fastest-growing cost line was Other operating costs (+137%). The quarter ended with a net loss of $1.1B, narrower than the previous quarter's $6.6B loss.

Operating cash flow was $0.44B. Non-cash charges added back $0.33B of depreciation and amortization and $0.06B of share-based compensation. Working capital and other items added $1.1B. Capital expenditures of $0.21B left free cash flow of $0.22B.

Questions

What was Centene's revenue in the fourth quarter 2025?

Centene (CNC) reported revenue of $49.7B for the fourth quarter 2025 (Q4 2025), +22% from a year earlier and +0.1% from the quarter before.

Was Centene profitable in the fourth quarter 2025?

Operating loss was $1.7B (-3.5% of revenue) and net loss $1.1B.

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Source: Centene 10-K on SEC EDGAR.