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Coya Therapeutics (COYA) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 16, 2026

Coya Therapeutics (COYA) reported revenue of $4.0M for the fourth quarter 2025 (Q4 2025), up 2,029-fold from a year earlier and +11% from the quarter before. Operating margin was -152.3%, net loss $5.7M (144.2% of revenue).

Revenue$4.0M
Year over year2,029×
Quarter over quarter+11%
Operating margin-152.3%
Net earnings−$5.7M

Coya Therapeutics, Q4 2025: revenue $4.0M (2,029× year over year), operating margin -152.3%, net loss $5.7M, operating cash flow −$1.0M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$4.0M+11%2,029×
Operating profit−$6.0M——
Net earnings−$5.7M——
Operating cash flow−$1.0M——

What changed

Revenue was $4.0M in Q4 2025, up 202769% year over year and up 11% from the previous quarter.

Operating costs exceeded revenue by $6.0M, an operating margin of -152.3%. Total costs grew 145% against revenue growth of 202769%. The fastest-growing cost line was Research & development (+155%). The quarter ended with a net loss of $5.7M, wider than the previous quarter's $2.1M loss.

Operating cash flow was −$1.0M. Non-cash charges added back $7K of depreciation and $1.1M of share-based compensation. Working capital and other items added $3.6M.

Questions

What was Coya Therapeutics' revenue in the fourth quarter 2025?

Coya Therapeutics (COYA) reported revenue of $4.0M for the fourth quarter 2025 (Q4 2025), up 2,029-fold from a year earlier and +11% from the quarter before.

Was Coya Therapeutics profitable in the fourth quarter 2025?

Operating loss was $6.0M (-152.3% of revenue) and net loss $5.7M.

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Source: Coya Therapeutics 10-K on SEC EDGAR.