Filing Flows › Charles River Laboratories International (CRL) › Q4 2025
Charles River Laboratories International (CRL) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Feb 18, 2026
Charles River Laboratories International (CRL) reported revenue of $994M for the fourth quarter 2025 (Q4 2025), -0.8% from a year earlier and -1% from the quarter before. Operating margin was -28.5%, net loss $276M (27.8% of revenue).
Charles River Laboratories International, Q4 2025: revenue $994M (-0.8% year over year), operating margin -28.5%, net loss $276M, operating cash flow $148M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $994M | -1% | -0.8% |
| Operating profit | −$283M | -312% | — |
| Net earnings | −$276M | -608% | — |
| Operating cash flow | $148M | -31% | -7% |
| Free cash flow | $58.6M | -67% | -30% |
What changed
Revenue was $994.2M in Q4 2025, down 1% year over year and down 1% from the previous quarter. DSA was the largest line at 60% of revenue.
Operating costs exceeded revenue by $283.4M, an operating margin of -28.5%. Total costs grew 9% against a revenue fall of 1%. The fastest-growing cost line was Other operating costs (+11%). The quarter ended with a net loss of $276.3M, after a profit of $55.6M the previous quarter.
Operating cash flow was $147.5M (down 7% year over year). Non-cash charges added back $78.3M of depreciation and amortization and $17.6M of share-based compensation. Working capital and other items added $327.9M. Capital expenditures of $89.0M left free cash flow of $58.6M.
Questions
What was Charles River Laboratories International's revenue in the fourth quarter 2025?
Charles River Laboratories International (CRL) reported revenue of $994M for the fourth quarter 2025 (Q4 2025), -0.8% from a year earlier and -1% from the quarter before.
Was Charles River Laboratories International profitable in the fourth quarter 2025?
Operating loss was $283M (-28.5% of revenue) and net loss $276M.
Source: Charles River Laboratories International 10-K on SEC EDGAR.