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Castle Biosciences (CSTL) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 5, 2025

Castle Biosciences (CSTL) reported revenue of $88.0M for the first quarter 2025 (Q1 2025), +21% from a year earlier and +2% from the quarter before. Operating margin was -31.7%, net loss $25.8M (29.4% of revenue).

Revenue$88.0M
Year over year+21%
Quarter over quarter+2%
Operating margin-31.7%
Net earnings−$25.8M

Castle Biosciences, Q1 2025: revenue $88.0M (+21% year over year), operating margin -31.7%, net loss $25.8M, operating cash flow −$6.0M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$88.0M+2%+21%
Operating profit−$27.9M——
Net earnings−$25.8M——
Operating cash flow−$6.0M——

What changed

Revenue was $88.0M in Q1 2025, up 21% year over year and up 2% from the previous quarter. Dermatologic was the largest line at 72% of revenue. Non-Dermatologic added $11.4M year over year (up 83%), 76% of the total change.

Operating costs exceeded revenue by $27.9M, an operating margin of -31.7%. Total costs grew 48% against revenue growth of 21%. The fastest-growing cost line was Other operating costs (+1161%). The quarter ended with a net loss of $25.8M, after a profit of $9.6M the previous quarter.

Operating cash flow was −$6.0M. Non-cash charges added back $29.8M of depreciation and amortization and $11.2M of share-based compensation. Working capital and other items used $21.1M. Capital expenditures of $4.7M exceeded it, leaving free cash flow of −$10.8M.

Questions

What was Castle Biosciences' revenue in the first quarter 2025?

Castle Biosciences (CSTL) reported revenue of $88.0M for the first quarter 2025 (Q1 2025), +21% from a year earlier and +2% from the quarter before.

Was Castle Biosciences profitable in the first quarter 2025?

Operating loss was $27.9M (-31.7% of revenue) and net loss $25.8M.

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Source: Castle Biosciences 10-Q on SEC EDGAR.