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Castle Biosciences (CSTL) Q2 2026 earnings results (second quarter 2026)

10-Q filed Jul 30, 2026

Castle Biosciences (CSTL) reported revenue of $104M for the second quarter 2026 (Q2 2026), +20% from a year earlier and +24% from the quarter before. Operating margin was -3.0%, net loss $2.1M (2.0% of revenue).

Revenue$104M
Year over year+20%
Quarter over quarter+24%
Operating margin-3.0%
Net earnings−$2.1M

Castle Biosciences, Q2 2026: revenue $104M (+20% year over year), operating margin -3.0%, net loss $2.1M, operating cash flow $15.2M. The chart follows the revenue to costs, profit and cash.

Q2 2026AmountQ/QY/Y
Revenue$104M+24%+20%
Operating profit−$3.1M——
Net earnings−$2.1M—-146%
Operating cash flow$15.2M—-27%
Free cash flow$6.6M—-43%

What changed

Revenue was $103.5M in Q2 2026, up 20% year over year and up 24% from the previous quarter. Non-Dermatologic was the largest line at 53% of revenue. Non-Dermatologic added $25.0M year over year (up 83%), 144% of the total change. Dermatologic declined 13%.

Operating costs exceeded revenue by $3.1M, an operating margin of -3.0%. Total costs grew 18% against revenue growth of 20%. The fastest-growing cost line was Cost of revenue (+34%). The quarter ended with a net loss of $2.1M, narrower than the previous quarter's $14.5M loss. Non-operating items added $1.4M, -82% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was $15.2M (down 27% year over year). Non-cash charges added back $4.1M of depreciation and amortization and $11.6M of share-based compensation. Working capital and other items added $1.6M. Capital expenditures of $8.7M left free cash flow of $6.6M.

Questions

What was Castle Biosciences' revenue in the second quarter 2026?

Castle Biosciences (CSTL) reported revenue of $104M for the second quarter 2026 (Q2 2026), +20% from a year earlier and +24% from the quarter before.

Was Castle Biosciences profitable in the second quarter 2026?

Operating loss was $3.1M (-3.0% of revenue) and net loss $2.1M.

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Source: Castle Biosciences 10-Q on SEC EDGAR.