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Cue Biopharma (CUE) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 14, 2026

Cue Biopharma (CUE) reported revenue of $5.7M for the first quarter 2026 (Q1 2026), up 14-fold from a year earlier and -74% from the quarter before. Operating margin was -94.1%, net loss $5.2M (91.1% of revenue).

Revenue$5.7M
Year over year14×
Quarter over quarter-74%
Operating margin-94.1%
Net earnings−$5.2M

Cue Biopharma, Q1 2026: revenue $5.7M (14× year over year), operating margin -94.1%, net loss $5.2M, operating cash flow −$10.9M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$5.7M-74%14×
Operating profit−$5.4M-371%—
Net earnings−$5.2M-427%—
Operating cash flow−$10.9M——

What changed

Revenue was $5.7M in Q1 2026, up 1251% year over year and down 74% from the previous quarter.

Operating costs exceeded revenue by $5.4M, an operating margin of -94.1%. Total costs fell 13% while revenue rose 1251%. The quarter ended with a net loss of $5.2M, after a profit of $1.6M the previous quarter.

Operating cash flow was −$10.9M. Non-cash charges added back $566K of depreciation and amortization and $48K of share-based compensation. Working capital and other items used $6.4M. Capital expenditures of $121K exceeded it, leaving free cash flow of −$11.1M.

Questions

What was Cue Biopharma's revenue in the first quarter 2026?

Cue Biopharma (CUE) reported revenue of $5.7M for the first quarter 2026 (Q1 2026), up 14-fold from a year earlier and -74% from the quarter before.

Was Cue Biopharma profitable in the first quarter 2026?

Operating loss was $5.4M (-94.1% of revenue) and net loss $5.2M.

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Source: Cue Biopharma 10-Q on SEC EDGAR.