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Cue Biopharma (CUE) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 12, 2025

Cue Biopharma (CUE) reported revenue of $2.1M for the third quarter 2025 (Q3 2025), -36% from a year earlier and -27% from the quarter before. Operating margin was -353.4%, net loss $7.4M (346.6% of revenue).

Revenue$2.1M
Year over year-36%
Quarter over quarter-27%
Operating margin-353.4%
Net earnings−$7.4M

Cue Biopharma, Q3 2025: revenue $2.1M (-36% year over year), operating margin -353.4%, net loss $7.4M, operating cash flow −$9.0M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$2.1M-27%-36%
Operating profit−$7.6M——
Net earnings−$7.4M——
Operating cash flow−$9.0M——

What changed

Revenue was $2.1M in Q3 2025, down 36% year over year and down 27% from the previous quarter.

Operating costs exceeded revenue by $7.6M, an operating margin of -353.4%. Total costs fell 20% while revenue fell 36%. The quarter ended with a net loss of $7.4M, narrower than the previous quarter's $8.5M loss.

Operating cash flow was −$9.0M. Non-cash charges added back $80K of depreciation and amortization and $1.5M of share-based compensation. Working capital and other items used $3.2M.

Questions

What was Cue Biopharma's revenue in the third quarter 2025?

Cue Biopharma (CUE) reported revenue of $2.1M for the third quarter 2025 (Q3 2025), -36% from a year earlier and -27% from the quarter before.

Was Cue Biopharma profitable in the third quarter 2025?

Operating loss was $7.6M (-353.4% of revenue) and net loss $7.4M.

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Source: Cue Biopharma 10-Q on SEC EDGAR.