Filing Flows › Cryoport (CYRX) › Q4 2025
Cryoport (CYRX) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Mar 5, 2026
Cryoport (CYRX) reported revenue of $45.5M for the fourth quarter 2025 (Q4 2025), +10% from a year earlier and +3% from the quarter before. Operating margin was -22.1%, net loss $11.6M (25.6% of revenue).
Cryoport, Q4 2025: revenue $45.5M (+10% year over year), operating margin -22.1%, net loss $11.6M, operating cash flow $919K. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $45.5M | +3% | +10% |
| Operating profit | −$10.0M | — | — |
| Net earnings | −$11.6M | — | — |
| Operating cash flow | $919K | -58% | — |
What changed
Revenue was $45.5M in Q4 2025, up 10% year over year and up 3% from the previous quarter. Product was the largest line at 45% of revenue.
Gross margin was 47.8%, up 0.7 points from a year earlier. Operating costs exceeded revenue by $10.0M, an operating margin of -22.1%. Operating expenses fell 2% while revenue rose 10%. The quarter ended with a net loss of $11.6M, wider than the previous quarter's $6.9M loss.
Operating cash flow was $919K. Non-cash charges added back $6.4M of depreciation and amortization and $2.4M of share-based compensation. Working capital and other items added $3.8M. Capital expenditures of $5.5M exceeded it, leaving free cash flow of −$4.5M.
Questions
What was Cryoport's revenue in the fourth quarter 2025?
Cryoport (CYRX) reported revenue of $45.5M for the fourth quarter 2025 (Q4 2025), +10% from a year earlier and +3% from the quarter before.
Was Cryoport profitable in the fourth quarter 2025?
Operating loss was $10.0M (-22.1% of revenue) and net loss $11.6M.
Source: Cryoport 10-K on SEC EDGAR.