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Cytokinetics (CYTK) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 7, 2025

Cytokinetics (CYTK) reported revenue of $66.8M for the second quarter 2025 (Q2 2025), up 268-fold from a year earlier and up 42-fold from the quarter before. Operating margin was -167.0%, net loss $134M (201.2% of revenue).

Revenue$66.8M
Year over year268×
Quarter over quarter42×
Operating margin-167.0%
Net earnings−$134M

Cytokinetics, Q2 2025: revenue $66.8M (268× year over year), operating margin -167.0%, net loss $134M, operating cash flow −$128M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$66.8M42×268×
Operating profit−$112M——
Net earnings−$134M——
Operating cash flow−$128M——

What changed

Revenue was $66.8M in Q2 2025, up 26715% year over year and up 4129% from the previous quarter. License and Milestone Revenues was the largest line at 96% of revenue. Collaboration Revenues added $2.2M year over year (up 1108%), 3% of the total change.

Operating costs exceeded revenue by $111.5M, an operating margin of -167.0%. Total costs grew 37% against revenue growth of 26715%. The fastest-growing cost line was Research & development (+38%). The quarter ended with a net loss of $134.4M, narrower than the previous quarter's $161.4M loss.

Operating cash flow was −$128.2M. Non-cash charges added back $2.3M of depreciation and amortization and $27.5M of share-based compensation. Working capital and other items used $23.7M. Capital expenditures of $4.1M exceeded it, leaving free cash flow of −$132.4M.

Questions

What was Cytokinetics' revenue in the second quarter 2025?

Cytokinetics (CYTK) reported revenue of $66.8M for the second quarter 2025 (Q2 2025), up 268-fold from a year earlier and up 42-fold from the quarter before.

Was Cytokinetics profitable in the second quarter 2025?

Operating loss was $112M (-167.0% of revenue) and net loss $134M.

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Source: Cytokinetics 10-Q on SEC EDGAR.