Filing Flows › Ginkgo Bioworks Holdings (DNA) › Q4 2025
Ginkgo Bioworks Holdings (DNA) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Feb 26, 2026
Ginkgo Bioworks Holdings (DNA) reported revenue of $33.4M for the fourth quarter 2025 (Q4 2025), -24% from a year earlier and -14% from the quarter before. Operating margin was -211.9%, net loss $80.8M (241.8% of revenue).
Ginkgo Bioworks Holdings, Q4 2025: revenue $33.4M (-24% year over year), operating margin -211.9%, net loss $80.8M, operating cash flow −$47.7M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $33.4M | -14% | -24% |
| Operating profit | −$70.8M | — | — |
| Net earnings | −$80.8M | — | — |
| Operating cash flow | −$47.7M | — | — |
What changed
Revenue was $33.4M in Q4 2025, down 24% year over year and down 14% from the previous quarter.
Operating costs exceeded revenue by $70.8M, an operating margin of -211.9%. Total costs fell 29% while revenue fell 24%. The quarter ended with a net loss of $80.8M, narrower than the previous quarter's $80.8M loss.
Operating cash flow was −$47.7M. Non-cash charges added back $13.7M of depreciation and amortization and $21.0M of share-based compensation. Capital expenditures of $5K exceeded it, leaving free cash flow of −$47.7M.
Questions
What was Ginkgo Bioworks Holdings' revenue in the fourth quarter 2025?
Ginkgo Bioworks Holdings (DNA) reported revenue of $33.4M for the fourth quarter 2025 (Q4 2025), -24% from a year earlier and -14% from the quarter before.
Was Ginkgo Bioworks Holdings profitable in the fourth quarter 2025?
Operating loss was $70.8M (-211.9% of revenue) and net loss $80.8M.