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Ginkgo Bioworks Holdings (DNA) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 26, 2026

Ginkgo Bioworks Holdings (DNA) reported revenue of $33.4M for the fourth quarter 2025 (Q4 2025), -24% from a year earlier and -14% from the quarter before. Operating margin was -211.9%, net loss $80.8M (241.8% of revenue).

Revenue$33.4M
Year over year-24%
Quarter over quarter-14%
Operating margin-211.9%
Net earnings−$80.8M

Ginkgo Bioworks Holdings, Q4 2025: revenue $33.4M (-24% year over year), operating margin -211.9%, net loss $80.8M, operating cash flow −$47.7M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$33.4M-14%-24%
Operating profit−$70.8M——
Net earnings−$80.8M——
Operating cash flow−$47.7M——

What changed

Revenue was $33.4M in Q4 2025, down 24% year over year and down 14% from the previous quarter.

Operating costs exceeded revenue by $70.8M, an operating margin of -211.9%. Total costs fell 29% while revenue fell 24%. The quarter ended with a net loss of $80.8M, narrower than the previous quarter's $80.8M loss.

Operating cash flow was −$47.7M. Non-cash charges added back $13.7M of depreciation and amortization and $21.0M of share-based compensation. Capital expenditures of $5K exceeded it, leaving free cash flow of −$47.7M.

Questions

What was Ginkgo Bioworks Holdings' revenue in the fourth quarter 2025?

Ginkgo Bioworks Holdings (DNA) reported revenue of $33.4M for the fourth quarter 2025 (Q4 2025), -24% from a year earlier and -14% from the quarter before.

Was Ginkgo Bioworks Holdings profitable in the fourth quarter 2025?

Operating loss was $70.8M (-211.9% of revenue) and net loss $80.8M.

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Source: Ginkgo Bioworks Holdings 10-K on SEC EDGAR.