Filing Flows › Dyadic International (DYAI) › Q4 2025
Dyadic International (DYAI) Q4 2025 earnings results (fourth quarter 2025)
10-K filed Mar 25, 2026
Dyadic International (DYAI) reported revenue of $566K for the fourth quarter 2025 (Q4 2025), -31% from a year earlier and -51% from the quarter before. Operating margin was -271.6%, net loss $1.6M (277.1% of revenue).
Dyadic International, Q4 2025: revenue $566K (-31% year over year), operating margin -271.6%, net loss $1.6M, operating cash flow −$1.8M. The chart follows the revenue to costs, profit and cash.
| Q4 2025 | Amount | Q/Q | Y/Y |
|---|---|---|---|
| Revenue | $566K | -51% | -31% |
| Operating profit | −$1.5M | — | — |
| Net earnings | −$1.6M | — | — |
| Operating cash flow | −$1.8M | — | — |
What changed
Revenue was $566K in Q4 2025, down 31% year over year and down 51% from the previous quarter. Grant was the largest line at 58% of revenue.
Operating costs exceeded revenue by $1.5M, an operating margin of -271.6%. Total costs fell 10% while revenue fell 31%. The fastest-growing cost line was Other operating costs (+29%). The quarter ended with a net loss of $1.6M, narrower than the previous quarter's $2.0M loss.
Operating cash flow was −$1.8M. Non-cash charges added back $192K of share-based compensation. Working capital and other items used $395K.
Questions
What was Dyadic International's revenue in the fourth quarter 2025?
Dyadic International (DYAI) reported revenue of $566K for the fourth quarter 2025 (Q4 2025), -31% from a year earlier and -51% from the quarter before.
Was Dyadic International profitable in the fourth quarter 2025?
Operating loss was $1.5M (-271.6% of revenue) and net loss $1.6M.