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Foghorn Therapeutics (FHTX) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 11, 2026

Foghorn Therapeutics (FHTX) reported revenue of $9.2M for the fourth quarter 2025 (Q4 2025), +224% from a year earlier and +13% from the quarter before. Operating margin was -258.2%, net loss $21.7M (234.3% of revenue).

Revenue$9.2M
Year over year+224%
Quarter over quarter+13%
Operating margin-258.2%
Net earnings−$21.7M

Foghorn Therapeutics, Q4 2025: revenue $9.2M (+224% year over year), operating margin -258.2%, net loss $21.7M, operating cash flow −$22.3M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$9.2M+13%+224%
Operating profit−$23.9M——
Net earnings−$21.7M——
Operating cash flow−$22.3M——

What changed

Revenue was $9.2M in Q4 2025, up 224% year over year and up 13% from the previous quarter.

Operating costs exceeded revenue by $23.9M, an operating margin of -258.2%. Total costs grew 23% against revenue growth of 224%. The quarter ended with a net loss of $21.7M, wider than the previous quarter's $15.8M loss.

Operating cash flow was −$22.3M. Non-cash charges added back $802K of depreciation and amortization and $2.2M of share-based compensation. Working capital and other items used $3.6M.

Questions

What was Foghorn Therapeutics' revenue in the fourth quarter 2025?

Foghorn Therapeutics (FHTX) reported revenue of $9.2M for the fourth quarter 2025 (Q4 2025), +224% from a year earlier and +13% from the quarter before.

Was Foghorn Therapeutics profitable in the fourth quarter 2025?

Operating loss was $23.9M (-258.2% of revenue) and net loss $21.7M.

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Source: Foghorn Therapeutics 10-K on SEC EDGAR.