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Monte Rosa Therapeutics (GLUE) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 6, 2025

Monte Rosa Therapeutics (GLUE) reported revenue of $12.8M for the third quarter 2025 (Q3 2025), +39% from a year earlier and -45% from the quarter before. Operating margin was -258.3%, net loss $27.1M (212.1% of revenue).

Revenue$12.8M
Year over year+39%
Quarter over quarter-45%
Operating margin-258.3%
Net earnings−$27.1M

Monte Rosa Therapeutics, Q3 2025: revenue $12.8M (+38% year over year), operating margin -258.3%, net loss $27.1M, operating cash flow $100M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$12.8M-45%+39%
Operating profit−$33.0M——
Net earnings−$27.1M——
Operating cash flow$100M——
Free cash flow$99.8M——

What changed

Revenue was $12.8M in Q3 2025, up 39% year over year and down 45% from the previous quarter.

Operating costs exceeded revenue by $33.0M, an operating margin of -258.3%. Total costs grew 28% against revenue growth of 39%. The fastest-growing cost line was Research & development (+33%). The quarter ended with a net loss of $27.1M, wider than the previous quarter's $12.3M loss.

Operating cash flow was $100.4M. Non-cash charges added back $2.7M of depreciation and amortization and $4.4M of share-based compensation. Working capital and other items added $120.4M. Capital expenditures of $651K left free cash flow of $99.8M.

Questions

What was Monte Rosa Therapeutics' revenue in the third quarter 2025?

Monte Rosa Therapeutics (GLUE) reported revenue of $12.8M for the third quarter 2025 (Q3 2025), +39% from a year earlier and -45% from the quarter before.

Was Monte Rosa Therapeutics profitable in the third quarter 2025?

Operating loss was $33.0M (-258.3% of revenue) and net loss $27.1M.

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Source: Monte Rosa Therapeutics 10-Q on SEC EDGAR.