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Grail (GRAL) Q2 2025 earnings results (second quarter 2025)

10-Q filed Aug 13, 2025

Grail (GRAL) reported revenue of $35.5M for the second quarter 2025 (Q2 2025), +11% from a year earlier and +12% from the quarter before. Operating margin was -446.9%, net loss $114M (320.7% of revenue).

Revenue$35.5M
Year over year+11%
Quarter over quarter+12%
Operating margin-446.9%
Net earnings−$114M

Grail, Q2 2025: revenue $35.5M (+11% year over year), operating margin -446.9%, net loss $114M, operating cash flow −$77.0M. The chart follows the revenue to costs, profit and cash.

Q2 2025AmountQ/QY/Y
Revenue$35.5M+12%+11%
Operating profit−$159M——
Net earnings−$114M——
Operating cash flow−$77.0M——

What changed

Revenue was $35.5M in Q2 2025, up 11% year over year and up 12% from the previous quarter. Screening revenue was the largest line at 97% of revenue. Screening revenue added $6.2M year over year (up 22%), 174% of the total change. Development services revenue declined 69%.

Operating costs exceeded revenue by $158.9M, an operating margin of -446.9%. Total costs fell 88% while revenue rose 11%. The quarter ended with a net loss of $114.0M, wider than the previous quarter's $106.2M loss.

Operating cash flow was −$77.0M. Non-cash charges added back $38.1M of depreciation and amortization and $14.2M of share-based compensation. Working capital and other items used $15.2M. Capital expenditures of $369K exceeded it, leaving free cash flow of −$77.3M.

Questions

What was Grail's revenue in the second quarter 2025?

Grail (GRAL) reported revenue of $35.5M for the second quarter 2025 (Q2 2025), +11% from a year earlier and +12% from the quarter before.

Was Grail profitable in the second quarter 2025?

Operating loss was $159M (-446.9% of revenue) and net loss $114M.

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Source: Grail 10-Q on SEC EDGAR.