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HCW Biologics (HCWB) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 31, 2026

HCW Biologics (HCWB) reported revenue of $27K for the fourth quarter 2025 (Q4 2025), -93% from a year earlier and +73% from the quarter before.

Revenue$27K
Year over year-93%
Quarter over quarter+73%
Operating margin—
Net earnings$719K

HCW Biologics, Q4 2025: revenue $27K (-93% year over year), net earnings $719K, operating cash flow −$3.4M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$27K+73%-93%
Operating profit−$4.5M——
Net earnings$719K——
Operating cash flow−$3.4M——

What changed

Revenue was $27K in Q4 2025, down 93% year over year and up 73% from the previous quarter.

Gross margin was 20.0%, unchanged from Q4 2024. Operating costs exceeded revenue by $4.5M, an operating margin of -16519.1%. Operating expenses grew 38% against a revenue fall of 93%. The fastest-growing cost line was Other operating costs (+988%). Net earnings were $719K. The effective tax rate was 0.0%. Non-operating items added $5.2M, 720% of pre-tax earnings, so the bottom line overstates operating performance.

Operating cash flow was −$3.4M. Non-cash charges added back $157K of depreciation and amortization and $9K of share-based compensation. Working capital and other items used $4.2M.

Questions

What was HCW Biologics' revenue in the fourth quarter 2025?

HCW Biologics (HCWB) reported revenue of $27K for the fourth quarter 2025 (Q4 2025), -93% from a year earlier and +73% from the quarter before.

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Source: HCW Biologics 10-K on SEC EDGAR.