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Filing Flows › Heron Therapeutics (HRTX) › Q1 2026 › vs Q4 2025

Heron Therapeutics (HRTX) Q1 2026 vs Q4 2025 (quarter over quarter)

Heron Therapeutics's revenue fell $5.9M (-14%) from $40.6M in Q4 2025 to $34.7M in Q1 2026. The biggest changes: CINVANTI −$2.4M (-10%); ZYNRELEF −$2.3M (-18%); SUSTOL −$781K (-59%).

Heron Therapeutics, Q1 2026: revenue $34.7M (-11% year over year), operating margin -13.7%, net loss $8.1M, operating cash flow −$1.5M. The chart draws each line against Q4 2025, the increases inside each band.

Heron Therapeutics: what changed, Q1 2026 vs Q4 2025Heron Therapeutics: what changed, Q1 2026 vs Q4 2025Working capital & other$12.0MCash used in operations−$7.6MNet loss$5.2MOperating cash sources$5.2MNet loss absorbed$5.2MCINVANTI−$2.4MZYNRELEF−$2.3MSales & marketing$2.1MResearch & development−$1.4MGeneral & admin−$1.3M

Every line

LineQ1 2026Q4 2025Change%
CINVANTI$20.5M$22.9M−$2.4M-10%
ZYNRELEF$10.2M$12.5M−$2.3M-18%
Aponvie$3.4M$3.8M−$419K-11%
SUSTOL$547K$1.3M−$781K-59%
Revenue$34.7M$40.6M−$5.9M-14%
Net loss$8.1M$3.0M$5.2M+175%
Costs & expenses$42.8M$43.5M−$720K-2%
Operating costs$39.5M$40.5M−$1.1M-3%
Interest & other, net$3.3M$3.0M$354K+12%
Cost of revenue$10.6M$11.1M−$481K-4%
Research & development$2.4M$3.7M−$1.4M-36%
Sales & marketing$14.3M$12.2M$2.1M+17%
General & admin$12.1M$13.5M−$1.3M-10%
Operating cash sources$8.1M$3.0M$5.2M+175%
Depreciation & amortization$529K$537K−$8K-1%
Share-based compensation$3.0M$2.2M$797K+37%
Working capital & other$3.1M−$8.9M$12.0M—
Cash used in operations$1.5M$9.2M−$7.6M-83%
Net loss absorbed$8.1M$3.0M$5.2M+175%

Questions

How much did Heron Therapeutics's revenue grow quarter over quarter in Q1 2026?

Heron Therapeutics's revenue fell $5.9M (-14%) from $40.6M in Q4 2025 to $34.7M in Q1 2026.

What drove Heron Therapeutics's revenue change in Q1 2026?

CINVANTI −$2.4M (-10%); ZYNRELEF −$2.3M (-18%); SUSTOL −$781K (-59%).

Q1 2026 results → · Compare in the interactive Sankey →