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SeaStar Medical Holding (ICU) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 25, 2026

SeaStar Medical Holding (ICU) reported revenue of $420K for the fourth quarter 2025 (Q4 2025), +527% from a year earlier and +130% from the quarter before. Operating margin was -718.1%, net loss $2.9M (691.4% of revenue).

Revenue$420K
Year over year+527%
Quarter over quarter+130%
Operating margin-718.1%
Net earnings−$2.9M

SeaStar Medical Holding, Q4 2025: revenue $420K (+527% year over year), operating margin -718.1%, net loss $2.9M, operating cash flow −$4.1M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$420K+130%+527%
Operating profit−$3.0M——
Net earnings−$2.9M——
Operating cash flow−$4.1M——

What changed

Revenue was $420K in Q4 2025, up 527% year over year and up 130% from the previous quarter.

Gross margin was 97.1%, down 2.9 points from Q4 2024. Operating costs exceeded revenue by $3.0M, an operating margin of -718.1%. Operating expenses fell 29% while revenue rose 527%. The quarter ended with a net loss of $2.9M, narrower than the previous quarter's $3.5M loss.

Operating cash flow was −$4.1M. Non-cash charges added back $70K of share-based compensation. Working capital and other items used $1.3M.

Questions

What was SeaStar Medical Holding's revenue in the fourth quarter 2025?

SeaStar Medical Holding (ICU) reported revenue of $420K for the fourth quarter 2025 (Q4 2025), +527% from a year earlier and +130% from the quarter before.

Was SeaStar Medical Holding profitable in the fourth quarter 2025?

Operating loss was $3.0M (-718.1% of revenue) and net loss $2.9M.

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Source: SeaStar Medical Holding 10-K on SEC EDGAR.