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Iovance Biotherapeutics (IOVA) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 7, 2026

Iovance Biotherapeutics (IOVA) reported revenue of $71.4M for the first quarter 2026 (Q1 2026), +45% from a year earlier and -18% from the quarter before. Operating margin was -113.5%, net loss $79.0M (110.7% of revenue).

Revenue$71.4M
Year over year+45%
Quarter over quarter-18%
Operating margin-113.5%
Net earnings−$79.0M

Iovance Biotherapeutics, Q1 2026: revenue $71.4M (+45% year over year), operating margin -113.5%, net loss $79.0M, operating cash flow −$72.1M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$71.4M-18%+45%
Operating profit−$81.0M——
Net earnings−$79.0M——
Operating cash flow−$72.1M——

What changed

Revenue was $71.4M in Q1 2026, up 45% year over year and down 18% from the previous quarter. Amtagvi was the largest line at 84% of revenue. Amtagvi added $16.7M year over year (up 38%), 75% of the total change.

Operating costs exceeded revenue by $81.0M, an operating margin of -113.5%. Total costs fell 11% while revenue rose 45%. The quarter ended with a net loss of $79.0M, wider than the previous quarter's $71.9M loss.

Operating cash flow was −$72.1M. Non-cash charges added back $2.8M of depreciation and amortization and $11.3M of share-based compensation. Working capital and other items used $7.1M. Capital expenditures of $6.6M exceeded it, leaving free cash flow of −$78.7M.

Questions

What was Iovance Biotherapeutics' revenue in the first quarter 2026?

Iovance Biotherapeutics (IOVA) reported revenue of $71.4M for the first quarter 2026 (Q1 2026), +45% from a year earlier and -18% from the quarter before.

Was Iovance Biotherapeutics profitable in the first quarter 2026?

Operating loss was $81.0M (-113.5% of revenue) and net loss $79.0M.

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Source: Iovance Biotherapeutics 10-Q on SEC EDGAR.