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Filing Flows › Karyopharm Therapeutics (KPTI) › Q1 2026 › vs Q1 2025

Karyopharm Therapeutics (KPTI) Q1 2026 vs Q1 2025 (year over year)

Karyopharm Therapeutics's revenue rose $5.1M (+17%) from $30.0M in Q1 2025 to $35.1M in Q1 2026. The biggest changes: Product +$8.1M (+39%); License and Other −$3.1M (-34%).

Karyopharm Therapeutics, Q1 2026: revenue $35.1M (+17% year over year), operating margin -76.3%, net loss $22.4M, operating cash flow −$22.7M. The chart draws each line against Q1 2025, the increases inside each band.

Karyopharm Therapeutics: what changed, Q1 2026 vs Q1 2025Karyopharm Therapeutics: what changed, Q1 2026 vs Q1 2025Operating cash sources−$16.9MCash used in operations−$16.3MWorking capital & other−$15.8MProduct$8.1MOther income, net−$5.5MLicense and Other−$3.1MCosts & expenses−$1.5MOperating costs−$1.4MNet loss−$1.1MNet loss absorbed−$1.1M

Every line

LineQ1 2026Q1 2025Change%
Product$29.2M$21.1M$8.1M+39%
License and Other$5.9M$9.0M−$3.1M-34%
Revenue$35.1M$30.0M$5.1M+17%
Other income, net$4.4M$9.8M−$5.5M-56%
Net loss$22.4M$23.5M−$1.1M-5%
Costs & expenses$61.8M$63.3M−$1.5M-2%
Operating costs$61.8M$63.3M−$1.4M-2%
Income tax$1K$36K−$35K-97%
Research & development$33.8M$34.6M−$821K-2%
SG&A$26.7M$27.4M−$668K-2%
Other operating costs$1.3M$1.3M$44K+3%
Operating cash sources$25.7M$42.6M−$16.9M-40%
Depreciation$12K$78K−$66K-85%
Share-based compensation$3.0M$3.6M−$553K-16%
Cash used in operations$22.7M$39.0M−$16.3M-42%
Net loss absorbed$22.4M$23.5M−$1.1M-5%
Working capital & other$3.4M$19.2M−$15.8M-82%

Questions

How much did Karyopharm Therapeutics's revenue grow year over year in Q1 2026?

Karyopharm Therapeutics's revenue rose $5.1M (+17%) from $30.0M in Q1 2025 to $35.1M in Q1 2026.

What drove Karyopharm Therapeutics's revenue change in Q1 2026?

Product +$8.1M (+39%); License and Other −$3.1M (-34%).

Q1 2026 results → · Compare in the interactive Sankey →