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Filing Flows › Karyopharm Therapeutics (KPTI) › Q2 2026 › vs Q1 2026

Karyopharm Therapeutics (KPTI) Q2 2026 vs Q1 2026 (quarter over quarter)

Karyopharm Therapeutics's revenue fell $1.6M (-5%) from $35.1M in Q1 2026 to $33.4M in Q2 2026. The biggest changes: License and Other −$3.2M (-55%); Product +$1.6M (+6%).

Karyopharm Therapeutics, Q2 2026: revenue $33.4M (-12% year over year), operating margin -67.4%, net loss $67.0M, operating cash flow −$24.9M. The chart draws each line against Q1 2026, the increases inside each band.

Karyopharm Therapeutics: what changed, Q2 2026 vs Q1 2026Karyopharm Therapeutics: what changed, Q2 2026 vs Q1 2026Interest & other, net$48.9MOperating cash sources$44.6MNet loss$44.6MNet loss absorbed$44.6MWorking capital & other$43.5MCosts & expenses$38.6MOperating costs−$5.9MResearch & development−$4.8MLicense and Other−$3.2MCash used in operations$2.2M

Every line

LineQ2 2026Q1 2026Change%
Product$30.8M$29.2M$1.6M+6%
License and Other$2.7M$5.9M−$3.2M-55%
Revenue$33.4M$35.1M−$1.6M-5%
Net loss$67.0M$22.4M$44.6M+199%
Costs & expenses$100M$61.8M$38.6M+62%
Operating costs$56.0M$61.8M−$5.9M-9%
Interest & other, net$44.5M−$4.4M$48.9M—
Research & development$29.0M$33.8M−$4.8M-14%
SG&A$25.9M$26.7M−$768K-3%
Other operating costs$1.1M$1.3M−$260K-19%
Operating cash sources$67.0M$22.4M$44.6M+199%
Share-based compensation$1.9M$3.0M−$1.1M-36%
Working capital & other$40.2M−$3.4M$43.5M—
Cash used in operations$24.9M$22.7M$2.2M+10%
Net loss absorbed$67.0M$22.4M$44.6M+199%

Questions

How much did Karyopharm Therapeutics's revenue grow quarter over quarter in Q2 2026?

Karyopharm Therapeutics's revenue fell $1.6M (-5%) from $35.1M in Q1 2026 to $33.4M in Q2 2026.

What drove Karyopharm Therapeutics's revenue change in Q2 2026?

License and Other −$3.2M (-55%); Product +$1.6M (+6%).

Q2 2026 results → · Compare in the interactive Sankey →