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Filing Flows › Karyopharm Therapeutics (KPTI) › R&D spending

Karyopharm Therapeutics (KPTI) R&D spending by quarter

Karyopharm Therapeutics' R&D spending was $29.0M in Q2 2026 (second quarter 2026), -14% from Q1 2026. Over the last 7 quarters it ranged from $27.7M (Q4 2025) to $34.6M (Q1 2025).

Karyopharm Therapeutics R&D spending by quarterKaryopharm Therapeutics R&D spending by quarter$33.3MQ4 2024$34.6MQ1 2025$32.8MQ2 2025$30.5MQ3 2025$27.7MQ4 2025$33.8MQ1 2026$29.0MQ2 2026
QuarterR&D spendingQ/QY/Y
Q2 2026$29.0M-14%-12%
Q1 2026$33.8M+22%-2%
Q4 2025$27.7M-9%-17%
Q3 2025$30.5M-7%—
Q2 2025$32.8M-5%—
Q1 2025$34.6M+4%—
Q4 2024$33.3M——

Q2 2026 at a glance

Karyopharm Therapeutics, Q2 2026: revenue $33.4M (-12% year over year), operating margin -67.4%, net loss $67.0M, operating cash flow −$24.9M. The chart follows the revenue to costs, profit and cash.

Questions

What is Karyopharm Therapeutics' R&D spending?

Karyopharm Therapeutics' R&D spending was $29.0M in Q2 2026 (second quarter 2026), -14% from Q1 2026.

How has Karyopharm Therapeutics' R&D spending changed?

Over the last 7 quarters it ranged from $27.7M (Q4 2025) to $34.6M (Q1 2025).

Q2 2026 results → · How Karyopharm Therapeutics makes money →