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Lipocine (LPCN) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 10, 2026

Lipocine (LPCN) reported revenue of $1.1M for the fourth quarter 2025 (Q4 2025), -67% from a year earlier and +900% from the quarter before. Operating margin was -219.6%, net loss $2.4M (206.9% of revenue).

Revenue$1.1M
Year over year-67%
Quarter over quarter+900%
Operating margin-219.6%
Net earnings−$2.4M

Lipocine, Q4 2025: revenue $1.1M (-67% year over year), operating margin -219.6%, net loss $2.4M, operating cash flow −$2.9M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$1.1M+900%-67%
Operating profit−$2.5M——
Net earnings−$2.4M——
Operating cash flow−$2.9M——

What changed

Revenue was $1.1M in Q4 2025, down 67% year over year and up 900% from the previous quarter.

Operating costs exceeded revenue by $2.5M, an operating margin of -219.6%. Total costs grew 88% against a revenue fall of 67%. The fastest-growing cost line was Research & development (+150%). The quarter ended with a net loss of $2.4M, narrower than the previous quarter's $3.2M loss.

Operating cash flow was −$2.9M. Non-cash charges added back $15K of depreciation and amortization and $53K of share-based compensation. Working capital and other items used $617K.

Questions

What was Lipocine's revenue in the fourth quarter 2025?

Lipocine (LPCN) reported revenue of $1.1M for the fourth quarter 2025 (Q4 2025), -67% from a year earlier and +900% from the quarter before.

Was Lipocine profitable in the fourth quarter 2025?

Operating loss was $2.5M (-219.6% of revenue) and net loss $2.4M.

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Source: Lipocine 10-K on SEC EDGAR.