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Macrogenics (MGNX) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 13, 2026

Macrogenics (MGNX) reported revenue of $20.8M for the first quarter 2026 (Q1 2026), +57% from a year earlier and -50% from the quarter before. Operating margin was -161.0%, net loss $36.8M (177.0% of revenue).

Revenue$20.8M
Year over year+57%
Quarter over quarter-50%
Operating margin-161.0%
Net earnings−$36.8M

Macrogenics, Q1 2026: revenue $20.8M (+58% year over year), operating margin -161.0%, net loss $36.8M, operating cash flow −$35.8M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$20.8M-50%+57%
Operating profit−$33.4M——
Net earnings−$36.8M——
Operating cash flow−$35.8M-183%—

What changed

Revenue was $20.8M in Q1 2026, up 57% year over year and down 50% from the previous quarter. Contract manufacturing was the largest line at 68% of revenue. Contract manufacturing added $7.9M year over year (up 129%), 104% of the total change. Collaborative and other agreements declined 91%.

Operating costs exceeded revenue by $33.4M, an operating margin of -161.0%. Total costs fell 3% while revenue rose 57%. The fastest-growing cost line was Other operating costs (+76%). The quarter ended with a net loss of $36.8M, wider than the previous quarter's $14.2M loss.

Operating cash flow was −$35.8M. Non-cash charges added back $1.7M of depreciation and amortization and $2.6M of share-based compensation. Working capital and other items used $3.4M. Capital expenditures of $344K exceeded it, leaving free cash flow of −$36.2M.

Questions

What was Macrogenics' revenue in the first quarter 2026?

Macrogenics (MGNX) reported revenue of $20.8M for the first quarter 2026 (Q1 2026), +57% from a year earlier and -50% from the quarter before.

Was Macrogenics profitable in the first quarter 2026?

Operating loss was $33.4M (-161.0% of revenue) and net loss $36.8M.

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Source: Macrogenics 10-Q on SEC EDGAR.