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Metagenomi Therapeutics (MGX) Q3 2025 earnings results (third quarter 2025)

10-Q filed Nov 12, 2025

Metagenomi Therapeutics (MGX) reported revenue of $8.7M for the third quarter 2025 (Q3 2025), -25% from a year earlier and +2% from the quarter before. Operating margin was -263.8%, net loss $20.4M (235.5% of revenue).

Revenue$8.7M
Year over year-25%
Quarter over quarter+2%
Operating margin-263.8%
Net earnings−$20.4M

Metagenomi Therapeutics, Q3 2025: revenue $8.7M (-25% year over year), operating margin -263.8%, net loss $20.4M, operating cash flow −$21.3M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$8.7M+2%-25%
Operating profit−$22.8M——
Net earnings−$20.4M——
Operating cash flow−$21.3M——

What changed

Revenue was $8.7M in Q3 2025, down 25% year over year and up 2% from the previous quarter.

Operating costs exceeded revenue by $22.8M, an operating margin of -263.8%. Total costs fell 7% while revenue fell 25%. The quarter ended with a net loss of $20.4M, wider than the previous quarter's $19.9M loss.

Operating cash flow was −$21.3M. Non-cash charges added back $1.3M of depreciation and $3.0M of share-based compensation. Working capital and other items used $5.2M. Capital expenditures of $74K exceeded it, leaving free cash flow of −$21.3M.

Questions

What was Metagenomi Therapeutics' revenue in the third quarter 2025?

Metagenomi Therapeutics (MGX) reported revenue of $8.7M for the third quarter 2025 (Q3 2025), -25% from a year earlier and +2% from the quarter before.

Was Metagenomi Therapeutics profitable in the third quarter 2025?

Operating loss was $22.8M (-263.8% of revenue) and net loss $20.4M.

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Source: Metagenomi Therapeutics 10-Q on SEC EDGAR.