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Mirum Pharmaceuticals (MIRM) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 6, 2026

Mirum Pharmaceuticals (MIRM) reported revenue of $160M for the first quarter 2026 (Q1 2026), +43% from a year earlier and +7% from the quarter before. Operating margin was -493.8%, net loss $790M (494.2% of revenue).

Revenue$160M
Year over year+43%
Quarter over quarter+7%
Operating margin-493.8%
Net earnings−$790M

Mirum Pharmaceuticals, Q1 2026: revenue $160M (+43% year over year), operating margin -493.8%, net loss $790M, operating cash flow −$229M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$160M+7%+43%
Operating profit−$789M——
Net earnings−$790M——
Operating cash flow−$229M-3871%—

What changed

Revenue was $159.9M in Q1 2026, up 43% year over year and up 7% from the previous quarter. Livmarli was the largest line at 71% of revenue. Livmarli added $40.6M year over year (up 55%), 84% of the total change.

Operating costs exceeded revenue by $789.5M, an operating margin of -493.8%. Total costs grew 649% against revenue growth of 43%. The fastest-growing cost line was Other operating costs (+2595%). The quarter ended with a net loss of $790.2M, wider than the previous quarter's $5.7M loss.

Operating cash flow was −$228.8M. Non-cash charges added back $6.9M of depreciation and amortization and $36.2M of share-based compensation. Working capital and other items added $518.3M. Capital expenditures of $664K exceeded it, leaving free cash flow of −$229.4M.

Questions

What was Mirum Pharmaceuticals' revenue in the first quarter 2026?

Mirum Pharmaceuticals (MIRM) reported revenue of $160M for the first quarter 2026 (Q1 2026), +43% from a year earlier and +7% from the quarter before.

Was Mirum Pharmaceuticals profitable in the first quarter 2026?

Operating loss was $789M (-493.8% of revenue) and net loss $790M.

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Source: Mirum Pharmaceuticals 10-Q on SEC EDGAR.