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Merck (MRK) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 24, 2026

Merck (MRK) reported revenue of $16.4B for the fourth quarter 2025 (Q4 2025), +5% from a year earlier and -5% from the quarter before. Operating margin was 20.9%, net earnings $3.0B (18.1% of revenue).

Revenue$16.4B
Year over year+5%
Quarter over quarter-5%
Operating margin20.9%
Net earnings$3.0B

Merck, Q4 2025: revenue $16.4B (+5% year over year), operating margin 20.9%, net earnings $3.0B, operating cash flow $2.9B. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$16.4B-5%+5%
Operating profit$3.4B-49%-18%
Net earnings$3.0B-49%-21%
Operating cash flow$2.9B-63%-17%
Free cash flow$1.8B-73%-27%

What changed

Revenue was $16.4B in Q4 2025, up 5% year over year and down 5% from the previous quarter.

Operating profit was $3.4B, a 20.9% margin (down 5.8 points year over year). Operating profit fell $0.75B even though revenue rose $0.78B versus a year earlier, so costs grew faster than sales. Total costs grew 13% against revenue growth of 5%. The fastest-growing cost line was Other operating costs (+262%). Net earnings were $3.0B, down 21% year over year. The effective tax rate was 13.4%.

Operating cash flow was $2.9B (down 17% year over year), 96% of net earnings. Non-cash charges added back $4.3B of depreciation and amortization and $0.20B of share-based compensation. Working capital and other items used $4.6B. Capital expenditures of $1.0B left free cash flow of $1.8B.

Questions

What was Merck's revenue in the fourth quarter 2025?

Merck (MRK) reported revenue of $16.4B for the fourth quarter 2025 (Q4 2025), +5% from a year earlier and -5% from the quarter before.

Was Merck profitable in the fourth quarter 2025?

Operating profit was $3.4B (20.9% of revenue) and net earnings $3.0B.

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Source: Merck 10-K on SEC EDGAR.