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Who owns Praxis Precision Medicines (PRAX) stock

301 funds reported Praxis Precision Medicines (PRAX) shares in their latest 13F filings, worth $12.7B in all. The largest holder is Jupiter Topco LLC ($1.1B). Last quarter 171 funds added to their stakes and 122 cut them. Members of Congress and other officials disclosed 2 trades (2 buys, 0 sales).

Largest holders of PRAX (13F)Largest holders of PRAX (13F)Jupiter Topco LLC$1.1BJanus Henderson Group$1.1BFMR LLC$776MBlackRock$768MPerceptive Advisors LLC$682MBaker Bros. Advisors LP$587MOrbis Allan Gray$512MVanguard Portfolio Management LLC$447MVanguard Group$431MVanguard Capital Management LLC$414M

Largest holders (13F)

FundSharesValueChangeQuarter
Jupiter Topco LLC3,421,374$1.1Bbase2026-06-30
Janus Henderson Group3,458,863$1.1Bincrease2026-03-31
FMR LLC2,316,907$776Mincrease2026-06-30
BlackRock2,292,585$768Mdecrease2026-06-30
Perceptive Advisors LLC2,035,986$682Munchanged2026-06-30
Baker Bros. Advisors LP1,753,198$587Munchanged2026-06-30
Orbis Allan Gray1,529,788$512Mdecrease2026-06-30
Vanguard Portfolio Management LLC1,335,185$447Mincrease2026-06-30
Vanguard Group1,460,933$431Mincrease2025-12-31
Vanguard Capital Management LLC1,235,299$414Mincrease2026-06-30
State Street1,026,443$344Mincrease2026-06-30
Adage Capital Partners GP, L.L.C.1,015,480$340Mincrease2026-06-30
Deerfield Management Company, L.P. (series C)963,351$323Munchanged2026-06-30
Driehaus Capital Management LLC959,048$321Mincrease2026-06-30
Price T Rowe Associates942,999$316Mincrease2026-06-30

Trades by Congress and other officials

DateWhoTradeAmount
2026-09-29Gilbert Cisnerospurchase$1K–$15K
2026-07-30Gilbert Cisnerospurchase$1K–$15K

Praxis Precision Medicines' latest quarter

Praxis Precision Medicines, Q4 2024: revenue $7.5M (14× year over year), operating margin -857.0%, net loss $58.7M, operating cash flow −$56.1M. The chart follows the revenue to costs, profit and cash.

Questions

Who owns the most PRAX stock?

By the latest 13F filings: Jupiter Topco LLC ($1.1B); Janus Henderson Group ($1.1B); FMR LLC ($776M); BlackRock ($768M); Perceptive Advisors LLC ($682M).

Has Congress traded PRAX stock?

Officials disclosed 2 trades on file: 2 buys and 0 sales. The latest: Gilbert Cisneros, purchase on 2026-09-29.

What is the short interest in PRAX?

3,921,934 shares were sold short at the 2026-10-15 settlement, -6.36% of the float.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.