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Who owns Prime Medicine (PRME) stock

170 funds reported Prime Medicine (PRME) shares in their latest 13F filings, worth $416M in all. The largest holder is Alphabet ($61.1M). Last quarter 72 funds added to their stakes and 84 cut them.

Largest holders of PRME (13F)Largest holders of PRME (13F)Alphabet$61.1MBlackRock$35.4MARK Investment Management LLC$30.8MState Street$28.0MVanguard Group$22.4MT. Rowe Price Investment Manageme…$19.3MVanguard Capital Management LLC$16.7MBalyasny Asset Management L.P.$14.6MGoldman Sachs Group$12.7MCasdin Capital, LLC$11.7M

Largest holders (13F)

FundSharesValueChangeQuarter
Alphabet16,562,498$61.1Munchanged2026-06-30
BlackRock9,602,041$35.4Mincrease2026-06-30
ARK Investment Management LLC8,348,746$30.8Mincrease2026-06-30
State Street7,576,460$28.0Mincrease2026-06-30
Vanguard Group6,467,872$22.4Mincrease2025-12-31
T. Rowe Price Investment Management5,237,332$19.3Mdecrease2026-06-30
Vanguard Capital Management LLC4,522,640$16.7Mincrease2026-06-30
Balyasny Asset Management L.P.3,969,082$14.6Mdecrease2026-06-30
Goldman Sachs Group3,430,518$12.7Mincrease2026-06-30
Casdin Capital, LLC3,167,175$11.7Munchanged2026-06-30
Woodline Partners LP3,003,904$11.1Mincrease2026-06-30
UBS Group AG2,794,689$10.3Mdecrease2026-06-30
Geode Capital Management, LLC2,712,446$10.0Mdecrease2026-06-30
MWG Management1,792,210$9.9Munchanged2025-09-30
Sumitomo Mitsui Trust Group2,412,984$8.9Mdecrease2026-06-30

Prime Medicine's latest quarter

Prime Medicine, Q4 2025: revenue $838K (-62% year over year), net loss $46.1M, operating cash flow −$37.3M. The chart follows the revenue to costs, profit and cash.

Questions

Who owns the most PRME stock?

By the latest 13F filings: Alphabet ($61.1M); BlackRock ($35.4M); ARK Investment Management LLC ($30.8M); State Street ($28.0M); Vanguard Group ($22.4M).

What is the short interest in PRME?

32,871,532 shares were sold short at the 2026-10-15 settlement, 2.35% of the float.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.