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Prothena Corp Public (PRTA) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Feb 27, 2026

Prothena Corp Public (PRTA) reported revenue of $21K for the fourth quarter 2025 (Q4 2025), -99% from a year earlier and -99% from the quarter before.

Revenue$21K
Year over year-99%
Quarter over quarter-99%
Operating margin—
Net earnings−$21.6M

Prothena Corp Public, Q4 2025: revenue $21K (-99% year over year), net loss $21.6M, operating cash flow −$23.3M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$21K-99%-99%
Operating profit−$24.2M——
Net earnings−$21.6M——
Operating cash flow−$23.3M——

What changed

Revenue was $21K in Q4 2025, down 99% year over year and down 99% from the previous quarter.

Operating costs exceeded revenue by $24.2M, an operating margin of -115252.4%. Total costs fell 64% while revenue fell 99%. The quarter ended with a net loss of $21.6M, narrower than the previous quarter's $36.5M loss.

Operating cash flow was −$23.3M. Non-cash charges added back $218K of depreciation and amortization and $7.1M of share-based compensation. Working capital and other items used $9.0M.

Questions

What was Prothena Corp Public's revenue in the fourth quarter 2025?

Prothena Corp Public (PRTA) reported revenue of $21K for the fourth quarter 2025 (Q4 2025), -99% from a year earlier and -99% from the quarter before.

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Source: Prothena Corp Public 10-K on SEC EDGAR.