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PTC Therapeutics (PTCT) Q1 2026 earnings results (first quarter 2026)

10-Q filed May 7, 2026

PTC Therapeutics (PTCT) reported revenue of $273M for the first quarter 2026 (Q1 2026), -77% from a year earlier and +66% from the quarter before. Operating margin was 16.5%, net loss $2.8M (1.0% of revenue).

Revenue$273M
Year over year-77%
Quarter over quarter+66%
Operating margin16.5%
Net earnings−$2.8M

PTC Therapeutics, Q1 2026: revenue $273M (-77% year over year), operating margin 16.5%, net loss $2.8M, operating cash flow −$59.0M. The chart follows the revenue to costs, profit and cash.

Q1 2026AmountQ/QY/Y
Revenue$273M+66%-77%
Operating profit$45.0M—-95%
Net earnings−$2.8M—-100%
Operating cash flow−$59.0M—-107%

What changed

Revenue was $272.6M in Q1 2026, down 77% year over year and up 66% from the previous quarter. Sephience was the largest line at 46% of revenue. Collaboration and license revenue lost $986.1M year over year (down 100%), 109% of the total change.

Operating profit was $45.0M, a 16.5% margin (down 66.0 points year over year). Total costs grew 11% against a revenue fall of 77%. The fastest-growing cost line was Other operating costs (+154%). The quarter ended with a net loss of $2.8M, narrower than the previous quarter's $135.0M loss. Net interest and other expense of $47.4M was the main reason.

Operating cash flow was −$59.0M. Non-cash charges added back $15.4M of depreciation and amortization and $23.4M of share-based compensation. Working capital and other items used $95.1M. Capital expenditures of $1.2M exceeded it, leaving free cash flow of −$60.2M.

Questions

What was PTC Therapeutics' revenue in the first quarter 2026?

PTC Therapeutics (PTCT) reported revenue of $273M for the first quarter 2026 (Q1 2026), -77% from a year earlier and +66% from the quarter before.

Was PTC Therapeutics profitable in the first quarter 2026?

Operating profit was $45.0M (16.5% of revenue) and net loss $2.8M.

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Source: PTC Therapeutics 10-Q on SEC EDGAR.