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Who owns Protagonist Therapeutics (PTGX) stock

327 funds reported Protagonist Therapeutics (PTGX) shares in their latest 13F filings, worth $9.2B in all. The largest holder is BlackRock ($1.3B). Last quarter 176 funds added to their stakes and 115 cut them.

Largest holders of PTGX (13F)Largest holders of PTGX (13F)BlackRock$1.3BRTW Investments, LP$620MVanguard Group$473MVanguard Portfolio Management LLC$445MWellington Management Group LLP$419MUBS Group AG$417MState Street$407MVanguard Capital Management LLC$350MJohnson & Johnson$345MJanus Henderson Group$305M

Largest holders (13F)

FundSharesValueChangeQuarter
BlackRock10,307,837$1.3Bincrease2026-06-30
RTW Investments, LP5,061,175$620Mincrease2026-06-30
Vanguard Group5,413,690$473Mincrease2025-12-31
Vanguard Portfolio Management LLC3,629,298$445Mincrease2026-06-30
Wellington Management Group LLP3,416,781$419Mdecrease2026-06-30
UBS Group AG3,399,221$417Mdecrease2026-06-30
State Street3,321,554$407Mincrease2026-06-30
Vanguard Capital Management LLC2,853,394$350Mincrease2026-06-30
Johnson & Johnson2,449,183$345Munchanged2026-09-30
Janus Henderson Group2,891,527$305Mincrease2026-03-31
Invesco2,340,667$287Mincrease2026-06-30
Price T Rowe Associates2,149,662$264Mincrease2026-06-30
Jupiter Topco LLC2,129,780$261Mbase2026-06-30
Geode Capital Management, LLC1,741,209$213Mincrease2026-06-30
Woodline Partners LP1,414,173$173Munchanged2026-06-30

Protagonist Therapeutics' latest quarter

Protagonist Therapeutics, Q3 2026: revenue $274M (58× year over year), operating margin 79.6%, net earnings $220M, operating cash flow −$23.2M. The chart follows the revenue to costs, profit and cash.

Questions

Who owns the most PTGX stock?

By the latest 13F filings: BlackRock ($1.3B); RTW Investments, LP ($620M); Vanguard Group ($473M); Vanguard Portfolio Management LLC ($445M); Wellington Management Group LLP ($419M).

What is the short interest in PTGX?

10,297,224 shares were sold short at the 2026-10-15 settlement, 10.19% of the float.

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Updated Nov 8, 2026. Read automatically from SEC filings and public data; errors are possible. Not investment advice.