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Pelthos Therapeutics (PTHS) Q4 2025 earnings results (fourth quarter 2025)

10-K filed Mar 19, 2026

Pelthos Therapeutics (PTHS) reported revenue of $9.4M for the fourth quarter 2025 (Q4 2025) and +27% from the quarter before. Operating margin was -127.8%, net loss $21.7M (230.7% of revenue).

Revenue$9.4M
Year over year—
Quarter over quarter+27%
Operating margin-127.8%
Net earnings−$21.7M

Pelthos Therapeutics, Q4 2025: revenue $9.4M, operating margin -127.8%, net loss $21.7M, operating cash flow −$6.3M. The chart follows the revenue to costs, profit and cash.

Q4 2025AmountQ/QY/Y
Revenue$9.4M+27%—
Operating profit−$12.0M——
Net earnings−$21.7M——
Operating cash flow−$6.3M——

What changed

Revenue was $9.4M in Q4 2025, up 27% from the previous quarter.

Operating costs exceeded revenue by $12.0M, an operating margin of -127.8%. The quarter ended with a net loss of $21.7M, wider than the previous quarter's $16.2M loss. Net interest and other expense of $16.6M was the main reason.

Operating cash flow was −$6.3M. Non-cash charges added back $1.8M of share-based compensation. Working capital and other items added $13.6M.

Questions

What was Pelthos Therapeutics' revenue in the fourth quarter 2025?

Pelthos Therapeutics (PTHS) reported revenue of $9.4M for the fourth quarter 2025 (Q4 2025) and +27% from the quarter before.

Was Pelthos Therapeutics profitable in the fourth quarter 2025?

Operating loss was $12.0M (-127.8% of revenue) and net loss $21.7M.

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Source: Pelthos Therapeutics 10-K on SEC EDGAR.