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Ultragenyx Pharmaceutical (RARE) Q1 2025 earnings results (first quarter 2025)

10-Q filed May 7, 2025

Ultragenyx Pharmaceutical (RARE) reported revenue of $139M for the first quarter 2025 (Q1 2025), +28% from a year earlier and -16% from the quarter before. Operating margin was -102.9%, net loss $151M (108.6% of revenue).

Revenue$139M
Year over year+28%
Quarter over quarter-16%
Operating margin-102.9%
Net earnings−$151M

Ultragenyx Pharmaceutical, Q1 2025: revenue $139M (+28% year over year), operating margin -102.9%, net loss $151M, operating cash flow −$166M. The chart follows the revenue to costs, profit and cash.

Q1 2025AmountQ/QY/Y
Revenue$139M-16%+28%
Operating profit−$143M——
Net earnings−$151M——
Operating cash flow−$166M——

What changed

Revenue was $139.0M in Q1 2025, up 28% year over year and down 16% from the previous quarter. Product was the largest line at 66% of revenue. Product added $29.0M year over year (up 46%), 96% of the total change.

Operating costs exceeded revenue by $143.0M, an operating margin of -102.9%. Total costs grew 3% against revenue growth of 28%. The fastest-growing cost line was Other operating costs (+65%). The quarter ended with a net loss of $151.0M, wider than the previous quarter's $133.2M loss.

Operating cash flow was −$166.0M. Non-cash charges added back $9.0M of depreciation and amortization and $40K of share-based compensation. Working capital and other items used $24.0M. Capital expenditures of $1.3M exceeded it, leaving free cash flow of −$167.3M.

Questions

What was Ultragenyx Pharmaceutical's revenue in the first quarter 2025?

Ultragenyx Pharmaceutical (RARE) reported revenue of $139M for the first quarter 2025 (Q1 2025), +28% from a year earlier and -16% from the quarter before.

Was Ultragenyx Pharmaceutical profitable in the first quarter 2025?

Operating loss was $143M (-102.9% of revenue) and net loss $151M.

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Source: Ultragenyx Pharmaceutical 10-Q on SEC EDGAR.