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Arcus Biosciences (RCUS) Q3 2025 earnings results (third quarter 2025)

10-Q filed Oct 28, 2025

Arcus Biosciences (RCUS) reported revenue of $26.0M for the third quarter 2025 (Q3 2025), -46% from a year earlier and -84% from the quarter before. Operating margin was -546.2%, net loss $135M (519.2% of revenue).

Revenue$26.0M
Year over year-46%
Quarter over quarter-84%
Operating margin-546.2%
Net earnings−$135M

Arcus Biosciences, Q3 2025: revenue $26.0M (-46% year over year), operating margin -546.2%, net loss $135M, operating cash flow −$97.0M. The chart follows the revenue to costs, profit and cash.

Q3 2025AmountQ/QY/Y
Revenue$26.0M-84%-46%
Operating profit−$142M——
Net earnings−$135M——
Operating cash flow−$97.0M——

What changed

Revenue was $26.0M in Q3 2025, down 46% year over year and down 84% from the previous quarter. License and Development Services Revenue was the largest line at 77% of revenue. License and Development Services Revenue lost $21.0M year over year (down 51%), 95% of the total change.

Operating costs exceeded revenue by $142.0M, an operating margin of -546.2%. Total costs grew 10% against a revenue fall of 46%. The fastest-growing cost line was Research & development (+15%). The quarter ended with a net loss of $135.0M, after a profit of $0K the previous quarter.

Operating cash flow was −$97.0M. Non-cash charges added back $2.0M of depreciation and amortization and $14.0M of share-based compensation. Working capital and other items added $22.0M.

Questions

What was Arcus Biosciences' revenue in the third quarter 2025?

Arcus Biosciences (RCUS) reported revenue of $26.0M for the third quarter 2025 (Q3 2025), -46% from a year earlier and -84% from the quarter before.

Was Arcus Biosciences profitable in the third quarter 2025?

Operating loss was $142M (-546.2% of revenue) and net loss $135M.

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Source: Arcus Biosciences 10-Q on SEC EDGAR.